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We observed reduced SPRTN auto-cleavage upon DPC induction in USP11 and USP7 double-knockdown and one cells, suggesting that in the lack of USP7 and USP11, SPRTN could possibly be deubiquitinated by VCPIP1, which is recruited to chromatin upon DPC induction

  • Post author:aftaka
  • Post published:February 28, 2022
  • Post category:Protein Ser/Thr Phosphatases

We observed reduced SPRTN auto-cleavage upon DPC induction in USP11 and USP7 double-knockdown and one cells, suggesting that in the lack of USP7 and USP11, SPRTN could possibly be deubiquitinated…

Continue ReadingWe observed reduced SPRTN auto-cleavage upon DPC induction in USP11 and USP7 double-knockdown and one cells, suggesting that in the lack of USP7 and USP11, SPRTN could possibly be deubiquitinated by VCPIP1, which is recruited to chromatin upon DPC induction

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