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Overcoming EZH2 Inhibitor Resistance for immunotherapy

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  • Post author:aftaka
  • Post published:November 22, 2022
  • Post category:LXR-like Receptors

922.15. (4-((S)-3-((S)-1-((5-(benzylcarbamoyl)-3-carbamoyl-[1,1-biphenyl]-3-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-2-(4-cyanobenzamido)-3-oxopropyl)phenyl bis(dimethylamino) phosphordiamidate (13bd) Phenol 12bd (70mg, 0.096mmol) was treated according to general process H, and purified by adobe flash column chromatography (1:1 CH2Cl2:(92:7:1 CH2Cl2:MeOH:NH4OH)) to yield final product…

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