HDACs

It comes mainly because no surprise, after that, that activating mutations in the gene occurring in tumor cells have an identical clinical impact to gene mutations, building them refractory both to cetuximab and panitumumab [6, 27, 45C47]

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It comes mainly because no surprise, after that, that activating mutations in the gene occurring in tumor cells have an identical clinical impact to gene mutations, building them refractory both…

Continue ReadingIt comes mainly because no surprise, after that, that activating mutations in the gene occurring in tumor cells have an identical clinical impact to gene mutations, building them refractory both to cetuximab and panitumumab [6, 27, 45C47]

All point mutations were generated by following a manufacturer’s instructions (QuikChange II, Agilent)

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All point mutations were generated by following a manufacturer's instructions (QuikChange II, Agilent). Protein expression and purification GST-GRK2RH, GST-p63RhoGEFDH/PHext, GST-TrioDH/PHext, GST-kalirinDH/PHext, GST-GAIP, and GST-RGS2 were expressed in BL21(DE3) transformed with…

Continue ReadingAll point mutations were generated by following a manufacturer’s instructions (QuikChange II, Agilent)

Mascola JR, Stiegler G, VanCott TC, Katinger H, Carpenter CB, Hanson CE, Beary H, Hayes D, Frankel SS, Birx DL, Lewis MG

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Mascola JR, Stiegler G, VanCott TC, Katinger H, Carpenter CB, Hanson CE, Beary H, Hayes D, Frankel SS, Birx DL, Lewis MG. the increase. T cells were broadly reactive and…

Continue ReadingMascola JR, Stiegler G, VanCott TC, Katinger H, Carpenter CB, Hanson CE, Beary H, Hayes D, Frankel SS, Birx DL, Lewis MG

All other data were analyzed using a two-tailed unpaired test to determine statistical significance between two experimental groups or a one-way ANOVA followed by a Tukey post-test to compare multiple groups, unless otherwise noted

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All other data were analyzed using a two-tailed unpaired test to determine statistical significance between two experimental groups or a one-way ANOVA followed by a Tukey post-test to compare multiple…

Continue ReadingAll other data were analyzed using a two-tailed unpaired test to determine statistical significance between two experimental groups or a one-way ANOVA followed by a Tukey post-test to compare multiple groups, unless otherwise noted